Transient receptor potential melastatin 6 and transient receptor potential melastatin 6/7 antagonists suppress colon adenocarcinoma HT-29 cells

Figure 6 Effects of Mg²⁺ channel inhibitors on migration of spheroid-derived HT-29 cells. A and B: Wounding area of spheroid (SP)-derived HT-29 cells treated with or without Co(III)hexamine; C and D: Wounding area of SP-derived HT-29 cells treated with or without 2-aminoethyl diphenylborinate; E and F: Wounding area of SP-derived HT-29 cells treated with or without Mesendogen. Scale bar = 200 μm. Co(III)hex: Co(III)hexamine; 2-APB: 2-aminoethyl diphenylborinate; ME: Mesendogen. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001 vs the corresponding control group at same time point (n = 6).