Transient receptor potential melastatin 6 and transient receptor potential melastatin 6/7 antagonists suppress colon adenocarcinoma HT-29 cells

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Dec 15, 2025; 17(12): 110736
Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.110736

Table 3 Methionine oxidation in transient receptor potential melastatin 6 and transient receptor potential melastatin 7 proteins

TRPM6		TRPM7
Parental HT-29	Spheroid-derived HT-29	Parental HT-29	Spheroid-derived HT-29
M33, M63, M133, M338, M370, M416, M618, M623, M625, M648, M657, M732, M768, M847, M864, M969, M984, M1020, 1061, M1076, M1093, M1162, M1278, M1183, M1434, M1436, M1575, M1879, M2020	M1, M33, M133, M244, M338, M370, M416, M444, M450, M618, M623, M625, M648, M657, M727, M734, M739, M768, M847, M969, M984, M1093, M1162, M1190, M1265, M1434, M1436, M1575, M1719, M1879, M1904, M1947, M2020	M43, M372, M632, M637, M649, M706, M742, M746, M782, M794, M812, M868, M878, M906 M991, M996, M1000, M1088, M1020, M1180, M1207, M1287, M1319, M1373, M1446, M1616, M1720, M1745	M130, M575, M591, M595, M649, M662, M704, M706, M741, M746, M773, M782, M812, M868, M991, M992, M996, M1000, M1180, M1207, M1287, M1318, M1373, M1446, M1528, M1561, M1616, M1720, M1745, M1788

TRPM: Transient receptor potential melastatin.

Citation: Kampuang N, Chamniansawat S, Pongkorpsakol P, Treveeravoot S, Thongon N. Transient receptor potential melastatin 6 and transient receptor potential melastatin 6/7 antagonists suppress colon adenocarcinoma HT-29 cells. World J Gastrointest Oncol 2025; 17(12): 110736
URL: https://www.wjgnet.com/1948-5204/full/v17/i12/110736.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i12.110736

Kampuang N, Chamniansawat S, Pongkorpsakol P, Treveeravoot S, Thongon N. Transient receptor potential melastatin 6 and transient receptor potential melastatin 6/7 antagonists suppress colon adenocarcinoma HT-29 cells. World J Gastrointest Oncol 2025; 17(12): 110736 [PMID: 41480213 DOI: 10.4251/wjgo.v17.i12.110736]

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