Investigating radiotherapy’s impact on intestinal perforation risk in gastrointestinal tumor patients treated with bevacizumab

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2025; 17(12): 110621
Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.110621

Table 1 Clinical efficacy in the two groups, n (%)

Group	CR	PR	SD	PD	Disease control rate	Total effectiveness
Bevacizumab + radiotherapy group (n = 35)	8 (22.86)	11 (31.43)	9 (25.71)	7 (20.00)	28 (80.00)	19 (54.29)
Bevacizumab only group (n = 35)	3 (8.57)	7 (20.00)	11 (31.43)	14 (40.00)	21 (60.00)	10 (28.57)
χ²	-	-	-	-	-	4.769
P value	-	-	-	-	-	0.029

CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease.

Citation: He WM, Li WS. Investigating radiotherapy’s impact on intestinal perforation risk in gastrointestinal tumor patients treated with bevacizumab. World J Gastrointest Oncol 2025; 17(12): 110621
URL: https://www.wjgnet.com/1948-5204/full/v17/i12/110621.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i12.110621

He WM, Li WS. Investigating radiotherapy’s impact on intestinal perforation risk in gastrointestinal tumor patients treated with bevacizumab. World J Gastrointest Oncol 2025; 17(12): 110621 [PMID: 41480214 DOI: 10.4251/wjgo.v17.i12.110621]

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