Early cancer diagnosis via interpretable two-layer machine learning of plasma extracellular vesicle long RNA

Figure 8 Extraction and classification of important genes. A: The top five genes in terms of weight in each probabilistic principal component analysis-based extracellular vesicle long RNA index calculation process; B: Classification of gene types; C: The 49 pancreatic ductal adenocarcinoma cancer-related genes identified in this study were compared with those reported in the literature. PDAC: Pancreatic ductal adenocarcinoma; lncRNA: Long non-coding RNA.