Secular trend in universal hepatocellular carcinoma prevention: Taiwan, Poland, and Belgium experience

Figure 2 Age-period-cohort effects of hepatocellular carcinoma in Taiwan, 2000-2019. The highest age effects were 243.99 in males aged 75-79 and 144.04 in females aged 80-84. The rate ratios of the period effects from 2000 to 2019 decreased for both males and females (1.03 to 0.79 and 1.07 to 0.72, respectively). The rate ratios of the cohort effects increased during 1915-1935 (1.02 to 1.36 in males and 1.04 to 1.54 in females), but continually decreased from 1935-1989 (1.36 to 0.22 in males and 1.54 to 0.20 in females). CIHi: Upper limit of 95% confidence interval; CILo: Lower limit of 95% confidence interval.