MicroRNAs in colorectal cancer: A comparative analysis of circulating and tissue microRNA levels

Table 3 MicroRNAs differentially expressed in tissue and plasma with an opposite trend

MicroRNA	Tissue paired (19 T_tissue vs 19 PT_tissue)	Plasma case-control (19 CRC_plasma vs 16 CTRL_plasma)
miR-145-5p	Decrease, FC = 0.08, P = 0.001	Increase, FC = 3.53, P < 0.001
miR-143-3p	Decrease, FC = 0.16, P = 0.001	Increase, FC = 5.52, P < 0.001
miR-125b-5p	Decrease, FC = 0.19, P = 0.001	Increase, FC = 2.74, P = 0.002
let-7e-5p	Decrease, FC = 0.49, P = 0.02	Increase, FC = 1.69, P = 0.009
let-7f-5p	Decrease, FC = 0.52, P = 0.002	Increase, FC = 2.71, P < 0.001
miR-215-5p	Decrease, FC = 0.55, P = 0.036	Increase, FC = 3.62, P = 0.006
miR-23b-3p	Decrease, FC = 0.56, P = 0.02	Increase, FC = 1.97, P = 0.002
let-7c-5p	Decrease, FC = 0.62, P = 0.005	Increase, FC = 1.89, P < 0.001
miR-18a-5p	Increase, FC = 2.65, P = 0.049	Decrease, FC = 0.71, P = 0.009

T: Tumoral; PT: Peritumoral; CTRL: Control; CRC: Colorectal cancer; FC: Fold change.