©The Author(s) 2025.
World J Gastrointest Oncol. Nov 15, 2025; 17(11): 109923
Published online Nov 15, 2025. doi: 10.4251/wjgo.v17.i11.109923
Published online Nov 15, 2025. doi: 10.4251/wjgo.v17.i11.109923
Figure 2 An illustrative map of the biological functions of Osteopontin.
OPN: Osteopontin; TGF-β: Transforming growth factor-beta; MMPs: Matrix metalloproteinases; CAFs: Cancer-associated fibroblasts; CD: Cluster of differentiation.
- Citation: Nian H, Bai Y, Wang HY, Yu H, Zhang ZL, Shi RH, Zhang S, Wu YB, Zhou DH, Du QC. Targeting the Osteopontin-regulated PI3K/AKT signaling pathway: A molecular approach to overcome drug resistance and metastasis in gastrointestinal tumors. World J Gastrointest Oncol 2025; 17(11): 109923
- URL: https://www.wjgnet.com/1948-5204/full/v17/i11/109923.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i11.109923