©The Author(s) 2025.
World J Gastrointest Oncol. Oct 15, 2025; 17(10): 110997
Published online Oct 15, 2025. doi: 10.4251/wjgo.v17.i10.110997
Published online Oct 15, 2025. doi: 10.4251/wjgo.v17.i10.110997
Table 2 Comparison of operational taxonomic unit numbers detected using multi- and single-region 16S rRNA gene sequencing in gastric cancer tissues
| Group | n | Genus | Species | ||
| Paraffinized tissue | Fresh tissue | Paraffinized tissue | Fresh tissue | ||
| Multi-region sequencing | 59 | 2.67 ± 0.58 | 2.33 ± 1.53 | 1.03 ± 0.35 | 0.67 ± 0.18 |
| Single-region sequencing | 59 | 74.21 ± 7.81 | 51.00 ± 16.09 | 32.33 ± 5.51 | 28.67 ± 9.07 |
| t value | - | 70.224 | 25.392 | 46.861 | 25.937 |
| P value | - | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
- Citation: Wu TT, Zhou X, Huang Q, Yang Q. Effectiveness of multi-region 16S rRNA gene sequencing in studying the microbiome of gastric cancer tissues. World J Gastrointest Oncol 2025; 17(10): 110997
- URL: https://www.wjgnet.com/1948-5204/full/v17/i10/110997.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i10.110997