Rectal neuroendocrine tumors in a Latin American population: Insights from a Peruvian national cancer institute

Table 7 Cox regression analysis of the effect of clinical and pathological characteristics on overall survival

Variables	Univariate			Multivariate
	HR	95%CI	P value	HR	95%CI	P value
Grade
G1	1.01			1.01
G2	19.42	2.34-161.2	0.006	21.89	1.01-472.41	0.049
Ki-67 as%
< 3	1.01
3-20	19.42	2.34-161.2	0.006
Tumor size in cm
≤ 1	1.01
> 1	3.39	0.94-12.16	0.062
Tumor size in cm
≤ 2	1.01			1.01
> 2	5.34	1.44-19.73	0.012	0.53	0.05-5.51	0.598
Classification N
N0	1.01			1.01
N1	4.39	1.38-13.95	0.012	1.34	0.18-9.92	0.774
Classification M
M0	1.01			1.01
M1	5.08	1.59-16.23	0.006	0.65	0.09-4.65	0.67
Disease stage
Localized	1.01
Advanced	16.22	2.07-127	0.008
Number of metastatic sites
None	1.01
≥ 1	16.22	2.07-127	0.008

¹1.0 was used as the reference group, indicates the reference category.

N: Node; M: Metastasis; HR: Hazard ratio; CI: Confidence interval.