Helicobacter pylori-induced miR-136 is a potential predictor of early-stage gastric cancer

Figure 3 Nuclear factor kappa-B regulated miR-136 expression after Helicobacter pylori infection. A and B: Helicobacter pylori induced a significant increase in the relative luciferase activity of wild-type reporter vector; C-F: Nuclear factor kappa-B inhibitor could reduce the upregulated expression of miRNA-136 induced by Helicobacter pylori. ^aP < 0.01; NS: Not significant; Wt: Wild-type reporter vector; Mut: Mutant reporter vector; Bay: Nuclear factor kappa-B inhibitor; HP: Helicobacter pylori; HP+: With Helicobacter pylori infection; HP-: Without Helicobacter pylori.