Curcumin for gastric cancer: Mechanism prediction via network pharmacology, docking, and in vitro experiments

doi:10.4251/wjgo.v16.i8.3635

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3635-3650
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3635

Table 1 Primer sequences

Genes	Primers (5' to 3')
ESR1	F: AGTGCCTTGTTGGATGCT
ESR1	R: TGCCAGGTTGGTCAGTAAG
EGFR	F: GGGTGCAGGAGAGGAGAA
EGFR	R: CTGGTTGTGGCAGCAGTC
CYP3A4	F: ATGGCACCGTAAGTGGAG
CYP3A4	R: TGGTGTTCTCAGGCACAG
MAPK14	F: AATACTGGGGAGGGGACA
MAPK14	R: GGCTTCATTCGTTTTCGTT
CYP1A2	F: AGAATGCCCTCAACACCTT
CYP1A2	R: CCTTGCTCACATGCTCCT
CYP2B6	F: GTCTTCCCCAGTCCTCATT
CYP2B6	R: AGTGCAGAATCCCACAGC
GAPDH	F: TGTGTCCGTCGTGGATCTGA
GAPDH	R: TTGCTGTTGAAGTCGCAGGAG

ESR1: Estrogen receptor 1; EGFR: Epidermal growth factor receptor; CYP3A4: Cytochrome P450 family 3 subfamily A member 4; MAPK14: Mitogen-activated protein kinase 14; CYP1A2: Cytochrome P450 family 1 subfamily A member 2; CYP2B6: Cytochrome P450 family 2 subfamily B member 6.

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Citation: Yang PH, Wei YN, Xiao BJ, Li SY, Li XL, Yang LJ, Pan HF, Chen GX. Curcumin for gastric cancer: Mechanism prediction via network pharmacology, docking, and in vitro experiments. World J Gastrointest Oncol 2024; 16(8): 3635-3650
URL: https://www.wjgnet.com/1948-5204/full/v16/i8/3635.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i8.3635

Yang PH, Wei YN, Xiao BJ, Li SY, Li XL, Yang LJ, Pan HF, Chen GX. Curcumin for gastric cancer: Mechanism prediction via network pharmacology, docking, and in vitro experiments. World J Gastrointest Oncol 2024; 16(8): 3635-3650 [PMID: 39171177 DOI: 10.4251/wjgo.v16.i8.3635]

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