Visualization analysis of research hotspots and trends on gastrointestinal tumor organoids

Table 5 Top ten articles with the strongest citation bursts

Strength	Tittle	Source	First author	Impact index per article1
46.9	Prospective derivation of a living organoid biobank of colorectal cancer patients	Cell	Marc van de Wetering	183.5
34.04	Organoid models of human and mouse ductal pancreatic cancer	Cell	Sylvia F Boj	132.1
31.15	Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium	Gastroenterology	Toshiro Sato	179.2
21.96	Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids	Nature Medicine	Mami Matano	81.2
20.92	Sequential cancer mutations in cultured human intestinal stem cells	Nature	Jarno Drost	76.6
17	Deterministic progenitor behavior and unitary production of neurons in the neocortex	Cell	Peng Gao	30.7
16.73	Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients	Cell Stem Cell	Gerald Schwank	89.8
16.27	Comprehensive molecular characterization of human colon and rectal cancer	Nature	Cancer Genome Atlas Network	507.3
16.04	Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture	Nature medicine	Xingnan Li	29.5
16.02	Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases	Proceedings of the National Academy of Sciences of the United States of America	Fleur Weeber	31.1

¹The impact index per article is presented based on Reference Citation Analysis.