METTL5 promotes gastric cancer progression via sphingomyelin metabolism

Figure 4 METTL5 overexpression promoted malignant phenotype in gastric cancer cells. A: Western blot verified the overexpression efficiency of METTL5 in AGS cells; B: The RNA expression of METTL5 in AGS cell with METTL5 overexpression; C: The RNA expression of TRMT112 in AGS cell with METTL5 overexpression; D: The Cell Counting Kit-8 assay detected the proliferation ability of AGS cell with METTL5 overexpression; E: Clone formation assay to detect the clone formation ability of AGS cell with METTL5 overexpression; F: The wound-healing motility assay to detect the migration ability of AGS cell with METTL5 overexpression; G: Transwell assay to detect the invasion ability of AGS cells with METTL5 overexpression. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.