Transcriptome sequencing reveals novel biomarkers and immune cell infiltration in esophageal tumorigenesis

doi:10.4251/wjgo.v16.i4.1500

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Apr 15, 2024 (publication date) through May 22, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1500-1513
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1500

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Figure 2 Differentially expressed gene analysis and identification of key genes in development of esophageal carcinogenesis. A-C: The volcano plots show the differentially expressed genes (DEGs) for low-grade intraepithelial neoplasia, high-grade intraepithelial neoplasia, and carcinoma (CA) compared to the normal, respectively; D and E: Venn diagrams of up-regulated and down-regulated DEGs; F: Heatmap of the 86 key genes. LGIN: Low-grade intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia; CA: Carcinoma; NOR: Normal; TPM: Transcript per Kilobase per Million mapped reads.

Citation: Sun JR, Chen DM, Huang R, Wang RT, Jia LQ. Transcriptome sequencing reveals novel biomarkers and immune cell infiltration in esophageal tumorigenesis. World J Gastrointest Oncol 2024; 16(4): 1500-1513
URL: https://www.wjgnet.com/1948-5204/full/v16/i4/1500.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i4.1500