Pathologically successful conversion hepatectomy for advanced giant hepatocellular carcinoma after multidisciplinary therapy: A case report and review of literature

Table 3 Summary of published case reports of conversion therapy in advanced hepatocellular carcinoma patients

Ref.	Age	Sex	Underlying liver disease	Tumor size	Symptom	Previous treatment	Pathological response rate
Wei et al[22]	67	Male	Hepatitis B	7.2 cm × 7.1 cm × 6.4 cm	Abdominal discomfort	HAIC, TACE, Immunotargeted therapy	PR
Ning et al[23]	48	Male	Hepatitis B	16.2 cm × 11.2 cm	Palpable mass	TACE, Immunotargeted therapy	PR
Ning et al[23]	54	Male	Hepatitis B	14.9 cm × 11.8 cm	Abdominal pain	TACE, Immunotargeted therapy	CR
Zhou et al[24]	69	Male	Hepatitis B	12.7 cm × 10.3 cm	None	HAIC, TAE, Immunotargeted therapy	PR
Wu et al[25]	41	Male	Hepatitis B	7.1 cm × 5.5 cm × 5.1 cm	Abdominal pain	Immunotargeted therapy	CR
Chen et al[26]	49	Male	Hepatitis B	7.1 cm × 5.5 cm	None	Immunotargeted therapy	PR
Chen et al[27]	52	Male	Hepatitis B	11.3 cm × 12.0 cm × 11.9 cm	Abdominal pain	TACE, Targeted therapy	CR
Chen et al[27]	42	Male	Hepatitis B	11.4 cm × 8.9 cm × 10.0 cm	None	HAIC, TACE, Targeted therapy	PR
Yano et al[28]	68	Male	None	7.2 cm in S1	None	Immunotargeted therapy	PR
Zhang et al[29]	67	Male	None	The largest was ≥ 10 cm	Epigastric distention	TACE, antiviral therapy	PR
Tomonari et al[30]	69	Male	Alcoholic cirrhosis	7.3 cm	Abdominal pain	TAE, targeted therapy	PR
Tomonari et al[30]	71	Female	Nonalcoholic steatohepatitis	5.8 cm in S3	None	TAE, targeted therapy	PR
Tomonari et al[30]	73	Male	Alcoholic cirrhosis	5.2 cm in S5	None	TAE, targeted therapy	PR

HAIC: Hepatic arterial infusion chemotherapy; TAE: Transcatheter arterial embolization; TACE: Transcatheter arterial chemoembolization; PR: Partial remission; CR: Complete remission.