Clinical and socioeconomic determinants of survival in biliary tract adenocarcinomas

Table 1 Distribution of demographic and clinical characteristics among types of biliary tract cancers, n (%)

Characteristics	Ampulla of Vater, n = 7268	Intrahepatic bile duct, n = 11466	Extrahepatic bile duct, n = 12869	Gallbladder, n = 15883
Sex
Female	3347 (46.1)	5560 (49.4)	6141 (47.7)	11446 (72.1)
Male	3921 (53.9)	5806 (50.6)	6728 (52.3)	4437 (27.9)
Race
White	5763 (79.3)	8957 (78.1)	10092 (78.4)	12530 (78.9)
American Indian/Alaska native	57 (0.8)	119 (1)	120 (0.9)	269 (1.7)
Asian or Pacific Islander	888 (12.2)	1513 (13.2)	1641 (12.8)	1467 (9.2)
Black	560 (7.7)	877 (7.7)	1016 (7.9)	1617 (10.2)
Ethnicity
Hispanic	1174 (16.2)	1548 (13.5)	1678 (13.0)	3071 (19.3)
Non-Hispanic	6094 (83.8)	9918 (86.5)	11191 (87.0)	12812 (80.7)
Age
≤ 60 yr	2040 (28.1)	3337 (29.1)	2881 (22.4)	3694 (23.3)
> 60 yr	5228 (71.9)	8129 (70.9)	9988 (77.6)	12189 (76.7)
Stage
Local	738 (10.2)	1641 (14.3)	1379 (10.7)	995 (6.3)
Regional	2522 (34.7)	2189 (19.1)	3025 (23.5)	3594 (22.6)
Distant	824 (11.3)	2859 (24.9)	2532 (19.7)	3607 (22.7)
Unknown/un-staged	3184 (43.8)	4777 (41.7)	5933 (46.1)	7687 (48.4)
Grade
Well differentiated, I	1016 (14.0)	478 (4.2)	1021 (7.9)	1805 (11.4)
Moderately differentiated, II	3039 (41.8)	1688 (14.7)	2415 (18.8)	4608 (29.0)
Poorly differentiated, III	1720 (23.7)	1631 (14.2)	1926 (15.0)	4769 (30.0)
Undifferentiated; anaplastic, IV	72 (1.0)	72 (0.6)	82 (0.6)	231 (1.5)
Unknown	1421 (19.5)	7597 (66.3)	7425 (57.7)	4470 (28.1)
Marital status
Married	4185 (57.6)	6449 (56.2)	7032 (54.6)	7664 (48.3)
Divorced	604 (8.3)	1071 (9.3)	1102 (8.6)	1399 (8.8)
Single, never married	907 (12.5)	1452 (12.7)	1522 (11.8)	1868 (11.8)
Widowed	1322 (18.2)	2094 (18.3)	2764 (21.5)	4345 (27.4)
Unknown	250 (3.4)	400 (3.5)	449 (3.5)	607 (3.8)
Yr of diagnosis
1975-1990	796 (11.0)	684 (6.0)	1675 (13.0)	3107 (19.6)
1991-2005	2691 (37.0)	3898 (34.0)	5513 (34.7)	5513 (34.7)
2006-2016	3781 (52.0)	6884 (60.0)	7117 (55.3)	7263 (45.7)
Chemotherapy
Yes	2245 (30.9)	4445 (38.8)	4134 (32.1)	4705 (29.6)
No/unknown	5023 (69.1)	7021 (61.2)	8735 (67.9)	11178 (70.4)
Surgery
Yes	1003 (13.8)	427 (3.7)	1245 (9.7)	1787 (11.3)
No/unknown	6265 (86.2)	11039 (96.3)	11624 (90.3)	14096 (88.7)
Radiation
Yes	1245 (17.2)	1604 (14.0)	2489 (19.4)	2183 (13.8)
No/unknown	6003 (82.8)	9831 (86.0)	10334 (80.6)	13664 (86.2)