Roles and application of exosomes in the development, diagnosis and treatment of gastric cancer

doi:10.4251/wjgo.v16.i3.630

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Mar 15, 2024 (publication date) through May 14, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Mar 15, 2024; 16(3): 630-642
Published online Mar 15, 2024. doi: 10.4251/wjgo.v16.i3.630

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Figure 2 The role of exosome in the initiation and development of gastric cancer. Exosomes affect tumorigenesis, epithelial-mesenchymal transformation, proliferation, invasion, angiogenesis, metastasis, immune escape and drug resistance of gastric cancer. EMT: Epithelial-to-mesenchymal transition; TAM: Tumor-associated macrophage; NK: Natural killer; FasL: Fas ligand; PD-L1: Programmed cell death-ligand 1; IL: Interleukin; CAFs: Cancer-associated fibroblasts; MDSC: Myeloid suppressor cell.

Citation: Guan XL, Guan XY, Zhang ZY. Roles and application of exosomes in the development, diagnosis and treatment of gastric cancer. World J Gastrointest Oncol 2024; 16(3): 630-642
URL: https://www.wjgnet.com/1948-5204/full/v16/i3/630.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i3.630