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©The Author(s) 2024.
World J Gastrointest Oncol. Feb 15, 2024; 16(2): 398-413
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.398
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.398
Figure 5 Effect of Prohibitin 1 expression on hepatocellular carcinoma cell apoptosis.
A-F: HepG2 and SMMC-7721 cells were transfected with pEGFP-PHB1 (A-C) or shRNA-PHB1 (D-F) for 48 h. Cell apoptosis was investigated using Annexin V-FITC and PI and was analysed by flow cytometry. The histograms present the mean percentage of apoptotic cells. The data are presented as the mean ± SD of three independent experiments with similar results. aP < 0.05 and bP < 0.01 vs control and empty vector/shRNA-control, respectively.
- Citation: Shi JJ, Wang YK, Wang MQ, Deng J, Gao N, Li M, Li YP, Zhang X, Jia XL, Liu XT, Dang SS, Wang WJ. Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro. World J Gastrointest Oncol 2024; 16(2): 398-413
- URL: https://www.wjgnet.com/1948-5204/full/v16/i2/398.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i2.398