Copyright
©The Author(s) 2024.
World J Gastrointest Oncol. Feb 15, 2024; 16(2): 314-330
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.314
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.314
Characteristic | Category | Low expression of ABCG2, n = 322 | High expression of ABCG2, n = 322 | P value |
T stage | T1 | 15 (2.3) | 5 (0.8) | 0.114 |
T2 | 54 (8.4) | 57 (8.9) | ||
T3 | 219 (34.2) | 217 (33.9) | ||
T4 | 33 (5.1) | 41 (6.4) | ||
N stage | N0 | 209 (32.7) | 159 (24.8) | < 0.001 |
N1 | 76 (11.9) | 77 (12.0) | ||
N2 | 36 (5.6) | 83 (13.0) | ||
M stage | M0 | 239 (42.4) | 236 (41.8) | 0.111 |
M1 | 36 (6.4) | 53 (9.4) | ||
Primary therapy outcome | PD | 12 (3.8) | 21 (6.7) | 0.305 |
SD | 2 (0.6) | 3 (1.0) | ||
PR | 10 (3.2) | 6 (1.9) | ||
CR | 129 (41.3) | 129 (41.3) | ||
Sex | Female | 143 (22.2) | 158 (24.5) | 0.269 |
Male | 179 (27.8) | 164 (25.5) | ||
CEA level | ≤ 5 | 127 (30.6) | 134 (32.3) | 0.986 |
> 5 | 74 (17.8) | 80 (19.3) | ||
Perineural invasion | No | 90 (38.3) | 85 (36.2) | 0.351 |
Yes | 26 (11.1) | 34 (14.5) | ||
Lymphatic invasion | No | 192 (33.0) | 158 (27.1) | 0.007 |
Yes | 100 (17.2) | 132 (22.7) | ||
History of colon polyps | No | 182 (32.8) | 195 (35.1) | 0.510 |
Yes | 92 (16.6) | 86 (15.5) | ||
Neoplasm type | Colon adenocarcinoma | 244 (37.9) | 234 (36.3) | 0.417 |
Rectum adenocarcinoma | 78 (12.1) | 88 (13.7) | ||
Age in yr, median (IQR) | 68.0 (59.0, 75.8) | 68.0 (57.3, 76.0) | 0.423 |
- Citation: Zheng L, Lu J, Kong DL. Expression of cyclin-dependent kinase 9 is positively correlated with the autophagy level in colon cancer. World J Gastrointest Oncol 2024; 16(2): 314-330
- URL: https://www.wjgnet.com/1948-5204/full/v16/i2/314.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i2.314