Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases

Table 2 Multivariate logistic regression analysis of risk factors for neoplastic transformation of gastric hyperplastic polyps

Risk factors	P value	OR	95%CI
Age
≤ 65 years		1
> 65 year	0.003	1.789	1.227-2.609
Sex
Female		1
Male	0.006	1.680	1.158-2.438
Number
Single	1
Multiple (n ≥ 2)	0.003	1.851	1.230-2.784
Polyp size
≤ 1 cm		1
1 cm-2 cm	< 0.001	3.565	2.177-5.838
> 2 cm	< 0.001	3.756	1.909-7.392
Endoscopic color-red	0.701	0.916	0.619-1.356
Mucosal erosion	0.271	0.75	0.454-1.255
Polyp lobulation	0.264	0.73	0.432-1.263
Mucosal roughness	0.128	1.38	0.912-2.093
Shape
Non-pedunculated		1
Pedunculated or semi-pedunculated	< 0.001	2.722	1.689-4.388
Location, n (%)
Upper third		1
Middle third	0.066	0.609	0.368-1.011
Lower third	0.055	1.624	0.968-2.724
Background gastric mucosa
Chronic superficial gastritis		1
Chronic atrophic gastritis	0.014	1.876	1.134-3.103
Gastritis with intraepithelial neoplasia	< 0.001	5.299	3.173-8.849
Autoimmune gastritis	< 0.001	2.672	1.559-4.579

OR: Odds ratio; CI: Confidence interval.