Establishing prognostic models for intrahepatic cholangiocarcinoma based on immune cells

Table 2 Cox regression analysis for factors affecting the 1-year survival of intrahepatic cholangiocarcinoma in 141 patients enrolled in cohorts

Variable	No. of participants (n = 141)	Univariate analysis HR (95%CI)	P value	Multivariate analysis HR (95%CI)	P value
AST			0.002		0.002
Normal	81	0.20 (0.07, 0.56)		0.18 (0.06, 0.53)
Abnormal	60	1		1
Child-Pugh			< 0.001		< 0.001
Group A	136	1		1
Group B	5	9.35 (2.74, 31.94)		68.29 (9.34, 499.16)
CD20			0.009		< 0.001
High	5	1		1
Low	136	0.19 (0.06, 0.64)		0.08 (0.02, 0.29)
Paired adjacent tissues CD20			0.08		-
High	90	1
Low	51	2.14 (0.91, 5.03)
CD4			0.14		-
High	65	1
Low	76	0.52 (0.21, 1.24)
Paired adjacent tissues CD4			0.39		0.05
High	75	1		1
Low	66	0.68 (0.28, 1.65)		0.39 (0.16, 0.98)
CD8			0.29		-
High	94	1
Low	47	1.59 (0.67, 3.78)
Paired adjacent tissues CD8			0.46		0.002
High	37	1		1
Low	104	7.75 (1.04, 57.78)		57.49 (4.44, 744.84)
CK			0.23		-
High	16	0.51 (0.17, 1.53)
Low	125	1
Paired adjacent tissues CK			0.07		-
High	133	1
Low	8	3.06 (0.90, 10.40)
CD68			0.12		-
High	9	0.38 (0.11, 1.29)
Low	132	1
Paired adjacent tissues CD68			0.10		-
High	52	0.49 (0.21, 1.15)
Low	89	1

AST: Aspartate aminotransferase.