Cellular senescence throws new insights into patient classification and pharmacological interventions for clinical management of hepatocellular carcinoma

Figure 4 Genetic alterations of three cellular senescence subtypes. A–C: Significant mutated genes in The Cancer Genome Atlas hepatocellular carcinomas stratified by cellular senescence subtypes; D–F: Copy number amplification plots in three subtypes. The green line denotes the significance threshold (q = 0.25); G–I: Copy number deletion plots in three subtypes.