MicroRNA-363-3p inhibits colorectal cancer progression by targeting interferon-induced transmembrane protein 1

Figure 3 Interferon-induced transmembrane protein 1 mediates the regulatory effects of microRNA-363-3p on clonogenic survival, proliferation and migration of colorectal cancer cells. A: Western blot analysis of interferon-induced transmembrane protein 1 expression in SW480 and SW480KO cells; B: Representative images of clonogenic survival of SW480 or SW480KO cells. Cells were transfected with antagomir-363-3p or antagomir-NC. The graph shows the number of colonies; C: Proliferation curve of SW480 or SW480KO cells. Cells were transfected with antagomir-363-3p or antagomir-NC; D: Representative images of the gaps at 0 and 24 h after scratching. SW480 or SW480KO cells were transfected with antagomir-363-3p or antagomir-NC. The graph shows the relative migration distance. The scale bar is 200 μm. The results were shown as the mean ± SD. ^aP < 0.05, ^bP < 0.01. NS: No significance; IFITM1: Interferon-induced transmembrane protein 1; NC: Negative control.