Potential of damage associated molecular patterns in synergising radiation and the immune response in oesophageal cancer

Figure 5 Expression of damage associated molecular patterns on the surface of peripheral blood and tumour-infiltrating T cells. The expression of HMGB1 and calreticulin was determined on the surface of peripheral blood and tumour-infiltrating A) CD45^- and CD45⁺ cells and B) CD3⁺, CD3⁺CD4⁺, CD3⁺CD8⁺, in treatment-naïve and post-treatment OAC whole blood (WB) (n = 14 pre-treatment, n = 10 post-treatment) and tumour biopsy tissue (Bx) (n = 10 pre-treatment, n = 9 post-treatment) ex vivo by flow cytometry. Wilcoxon rank test, ^aP < 0.05, ^bP < 0.001. Treatments: FLOT n = 5 and CROSS n = 5.