Mitophagy-related gene signature predicts prognosis, immune infiltration and chemotherapy sensitivity in colorectal cancer

Figure 1 Grouping of mitophagy-related clusters in colorectal cancer. A: Expression correlation among mitophagy-related genes; B: The cophenetic plot of NMF clustering analyses; C: Heatmap showing three clusters were identified, along with the optimal value for consensus clustering; D: Principal component analysis of three mitophagy-related clusters; E: Kaplan-Meier curves for survival rate of three clusters showing patients in cluster III have the best prognosis (P = 0.0057). The P value was calculated using the log-rank test; F: Alluvial diagram of clusters shows patients in cluster III tend to be early-stage. NMF: Nonnegative Matrix Factorization.