Possible mechanisms associated with immune escape and apoptosis on anti-hepatocellular carcinoma effect of Mu Ji Fang granules

Figure 6 Mu Ji Fang Granules modulated the Transforming growth factor β1/ Mothers against decapentaplegic homolog signaling pathway and improved the expression of immune and apoptotic cytokines in HepG2 cells. A: Relative expression of Transforming growth factor β1, Mothers against decapentaplegic homolog (SMAD) 2, p-SMAD2, SMAD4, and SMAD7 protein; B: Relative expression of Tumor necrosis factor α and Interferon gamma mRNA; C: Relative expression of Bax, and Bcl2 mRNA (n = 4). Data are shown as the mean ± standard deviation. ^aP < 0.01 vs Control [Mu Ji Fang Granules (MJF) 0 mg/mL]. ^bP < 0.01 vs MJF 10 mg/mL.