Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth

Figure 4 Dopamine and cyclic adenosine monophosphate regulated phosphoprotein with an apparent Mr of 32000 reduces apoptosis in colorectal cancer cells. A and B: The apoptotic capabilities of cells in HCT116 and SW480 cells with dopamine and cyclic adenosine monophosphate regulated phosphoprotein with an apparent Mr of 32000 (DARPP-32) overexpression detected by analysis of cellular apoptosis; C and D: The apoptotic capabilities of cells in HT-29 and LOVO cells with DARPP-32 knockdown small interfering RNA (siRNA) detected by analysis of cell apoptosis. ^aP < 0.05; ^bP < 0.01. NC: Negative control.