Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth

Figure 3 Dopamine and cyclic adenosine monophosphate regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer proliferation in vivo. A: Dopamine and cyclic adenosine monophosphate regulated phosphoprotein with an apparent Mr of 32000 (DARPP-32)-overexpressing HCT116 cells were subcutaneously implanted into the shoulders of naked mice (n = 5) to assess proliferative potential; B: After injection, carcinoma volumes were measured in the negative control (NC) group and DARPP-32 group; C: DARPP-32 and Ki67 immune staining were performed on tumor tissues from the NC and DARPP-32 groups by immunohistochemistry (blue scale bars, 100 μm; black scale bars, 50 μm). ^aP < 0.05; ^cP < 0.001.