Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA vaccine development

doi:10.4251/wjgo.v15.i10.1717

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Oct 15, 2023 (publication date) through Jun 1, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2023; 15(10): 1717-1738
Published online Oct 15, 2023. doi: 10.4251/wjgo.v15.i10.1717

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Figure 9 Identification of potential biomarkers for mRNA vaccines. A: Differential distribution of module eigengenes among distinct hepatocellular carcinoma immune subtypes; B: Heatmap of module trait relationships; C: Dot plot showing the top 10 GO terms in the yellow module; D: Dot plot showing the top 10 KEGG terms in the yellow module; E and F: Kaplan-Meier plots showing overall survival (E) and recurrence-free survival (F) of the yellow module prognostic gene expression score; G: Distribution of six previously reported pancancer immune subtypes among IS1-IS4. ^dP value < 0.0001; NS: Not significant; HR: Hazard ratio.

Citation: Lu TL, Li CL, Gong YQ, Hou FT, Chen CW. Identification of tumor antigens and immune subtypes of hepatocellular carcinoma for mRNA vaccine development. World J Gastrointest Oncol 2023; 15(10): 1717-1738
URL: https://www.wjgnet.com/1948-5204/full/v15/i10/1717.htm
DOI: https://dx.doi.org/10.4251/wjgo.v15.i10.1717