Influence of SCENIC recommendations on terminology used for histopathologic diagnosis of inflammatory bowel disease-associated dysplasia

Table 1 Histopathologic diagnoses of polyps and polypoid lesions detected during surveillance colonoscopies in ulcerative colitis patients during pre-SCENIC (2012-2014) and post-SCENIC (2016-2018) periods

Histopathologic diagnosis	Pre-SCENIC (n = 347)	Post-SCENIC (n = 419)
Adenocarcinoma	3	3
TA	32	80
TVA	2	17
VA	0	2
Adenoma with HGD	2	2
LGD	14	1
LGD with focal HGD	0	1
HGD	2	1
Polypoid LGD	1	0
LGD with tubulovillous features	2	0
Adenomatous change/LGD	2	0
Adenomatous change with focal HGD	1	0
DALM	1	0
Combined serrated and low-grade adenomatous features	1	0
IND	14	6
HP	55	63
SSA/P	9	22
TSA	0	1
Hyperplastic change	51	81
Serrated epithelial change	1	0
Inflammatory polyp/pseudopolyp	143	96
Benign lymphoid aggregate	5	17
Well-differentiated NET	0	1
Pneumatosis intestinalis	0	1
Mucosal prolapse	0	2
Collagenous colitis	0	1
Submucosal giant cells	1	0
Atypical epithelial proliferation	0	1
Polypoid normal mucosa	4	20
Branching crypts	1	0

SCENIC: Surveillance for Colorectal Endoscopic Neoplasia Detection and Management in Inflammatory Bowel Disease Patients; UC: Ulcerative colitis; TA: Tubular adenoma; TVA: Tubulovillous adenoma; VA: Villous adenoma; LGD: Low-grade dysplasia; HGD: High-grade dysplasia; DALM: Dysplasia-associated lesion or mass; IND: Indefinite for dysplasia; HP: Hyperplastic polyp; SSA/P: Sessile serrated adenoma/polyp; TSA: Traditional serrated adenoma; NET: Neuroendocrine tumor.