Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors

doi:10.4251/wjgo.v14.i7.1337

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2022; 14(7): 1337-1347
Published online Jul 15, 2022. doi: 10.4251/wjgo.v14.i7.1337

Table 2 Characteristics of laterally spreading tumor subtypes

	G-NM (n = 152)	G-H (n = 61)	NG-PD (n = 62)	NG-FE (n = 66)
Size, median (IQR), cm	2.5 (1.8-4.0)	1.8 (1.5-2.4)	1.8 (1.5-2.5)	1.5 (1.3-1.9)
Location, n (%)
Right-sided colon	61 (40.1)	42 (68.9)	32 (51.6)	44 (66.7)
Caecum	25 (16.4)	16 (26.2)	4 (6.4)	4 (6.1)
Ascending colon	31 (20.4)	19 (31.1)	12 (19.4)	26 (39.4)
Transverse colon	5 (3.3)	7 (11.5)	16 (25.8)	14 (21.2)
Descending colon	5 (3.3)	3 (4.9)	5 (8.1)	9 (13.6)
Rectosigmoid	86 (56.6)	16 (26.2)	25 (40.3)	13 (19.7)
Sigmoid	21 (13.8)	4 (6.6)	11 (17.7)	9 (13.6)
Rectum	65 (42.8)	12 (19.7)	14 (22.6)	4 (6.1)
HGD/carcinoma rate, n (%)	117 (77.0)	18 (29.5)	53 (85.5)	16 (24.2)
Carcinoma in situ, n (%)	106 (69.7)	18 (29.5)	35 (56.4)	14 (21.2)
SMI rate, n (%)	11 (7.2)	0 (0)	18 (29.0)	2 (3.0)
Deep SMI rate, n (%)	4 (2.6)	0 (0)	8 (12.9)	0 (0)
Endoscopically unresectable, n (%)	7 (4.6)	0 (0)	9 (14.5)	0 (0)

LST: Laterally spreading tumor; G-NM: Granular nodular mixed; G-H: Granular homogenous; NG-FE: Non-granular flat elevated; NG-PD: Non-granular pseudodepressed; IQR: Interquartile range; HGD: High-grade dysplasia; SMI: Submucosal invasion.

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Citation: Hao XW, Li P, Wang YJ, Ji M, Zhang ST, Shi HY. Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors. World J Gastrointest Oncol 2022; 14(7): 1337-1347
URL: https://www.wjgnet.com/1948-5204/full/v14/i7/1337.htm
DOI: https://dx.doi.org/10.4251/wjgo.v14.i7.1337

Hao XW, Li P, Wang YJ, Ji M, Zhang ST, Shi HY. Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors. World J Gastrointest Oncol 2022; 14(7): 1337-1347 [PMID: 36051097 DOI: 10.4251/wjgo.v14.i7.1337]

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