Neoadjuvant therapy in resectable pancreatic cancer: A promising curative method to improve prognosis

Table 5 Comparison of tumor size between the upfront surgery group and the neoadjuvant therapy plus surgery group

Ref.	Country	NCT number/Name	Variable	Upfront surgery	NAT plus surgery	P value
Golcher et al[7]	Germany	NCT00335543	Tumoral diameter (cm)	NM	NM	NM
			T1-2 stage	2	4	NM
			T3-4 stage	21	15	NM
Versteijne et al[8]	Netherlands	PREOPANC	Tumoral diameter (cm)	NM	NM	NM
			T1-2 stage	NM	NM	NM
			T3-4 stage	NM	NM	NM
Casadei et al[9]	Italy	-	Tumoral diameter (cm)	NM	NM	NM
			T1-2 stage	0	9	0.016
			T3-4 stage	20	8
Reni et al[10]	Italy	PACT-15	Tumoral diameter (cm)	2.1-2.5	2	NM
			T1-2 stage	3	5	NM
			T3-4 stage	46	22	NM

NAT: Neoadjuvant therapy; NM: Not mentioned.