Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model

Figure 1 Hydrogen, 5-fluorouracil and their combination reduced tumor growth and tumor weight in a murine model of colorectal cancer. A: Tumor size; B: Tumor weight change in mice treated with hydrogen-rich water (HRW), 5-fluorouracil (5-FU) and their combination. P < 0.05 and P < 0.001 compared to control, P < 0.01 compared to 5-FU, P < 0.05 compared to HRW and P < 0.05, P < 0.01 and P < 0.001 compared to combination groups; n = 6 per group. a: P < 0.05 compare to control; b: P < 0.01 compare to control; c: P < 0.001 compare to control; d: P < 0.05 compare to H₂; e: P < 0.01 compare to 5-FU. H₂: Hydrogen; 5-FU: 5-fluorouracil.