Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival

Table 1 Baseline characteristics of patients included in this study

Characteristics		Frequency	%
All patients (n = 65)
Age (yr) ± SD		73.54 ± 9.51
(range)		(52-92)
Gender
Female		29	44.62
Male		36	55.38
Tumour localisation
Right colorectal cancer		43	66.15
Caecum		13	30.23
Ascending colon		23	53.49
Transverse colon		7	16.28
Left colorectal cancer		22	33.85
Descending colon		11	50.00
Sigma		11	50.00
Emergency surgery
Yes		1	1.54
No		64	98.46
Surgical procedure
Laparoscopic hemicolectomy		48	73.85
Open hemicolectomy		17	26.15
Development at surgery
Non-metastasised		37	56.92
Metastases		28	43.08
Liver synchronous		13	46.43
Liver metachronous		8	28.57
Other organs		13	46.43
MMR status
pMMR		56	86.15
dMMR		5	7.69
Unknown		4	6.15
TNM stage
0		3	4.62
I		7	10.77
IIA		21	32.31
IIB		5	7.69
IIIA		2	3.08
IIIB		8	12.31
IIIC		5	7.69
IV		1	1.54
IVA		10	15.38
IVB		3	4.62
Adjuvant chemotherapy
Yes		30	46.15
No		35	53.85
Blood leukocytes counting (× 103/μL), (normal range)	RCRC	LCRC	P value
White blood cells count (3.6-10.5)	7.41 (3.52-16.2)	8.19 (4.83-15.8)	0.271
Lymphocytes (1.1-4.5)	1.77 (0.46-4.46)	2.04 (0.32-4.87)	0.235
Monocytes (0.1-0.9)	0.54 (0.20-1.26)	0.50 (0.22-1.11)	0.493
Neutrophils (1.5-7.7)	4.86 (1.76-15.3)	5.34 (2.96-13.0)	0.480
Platelets (150-370)	275.65 (101.0-602.0)	272.41 (142.0-725.0)	0.910
LMRb	3.54 (0.42-7.96)	4.64 (0.58-11.88)	0.046
NLRb	3.65 (0.69-25.93)	4.61 (0.93-30.66)	0.481
PLRb	188.58 (52.24-551.22)	213.93 (29.16-1187.50)	0.585

TNM: Tumour-nodes-metastasis classification; MMR: DNA mismatch repair; pMMR: Proficient MMR; dMMR: Deficient MMR; LMR: Lymphocyte-to-monocyte ratio; NLR: Neutrophil-to-lymphocytes ratio; PLR: Platelet-to-lymphocyte ratio; RCRC: Right-sided colorectal cancer; LCRC: Left-sided colorectal cancer; SD: Standard deviation; b: Blood.