Review of incomplete macroscopic resections (R2) in rectal cancer: Treatment, prognosis and future perspectives

Table 1 Studies that have presented survival data for patients with R2 resections

Ref.	n	Survival
Hermanek et al[56], 2000	86	MS 4.7 mo (1.8-12.2)
Wiig et al[57], 2002	24	OS 5 yr 0%
Treiber et al[58], 2004	20	CL 3 yr 29%
Landmann et al[59], 2005	19	MS < 12 mo OS 5 yr 0%
Dresen et al[60], 2008	36	OS 3 yr 24.1%
Rahbari et al[21], 2011	13	MS 23 mo 23.1%
Bhangu et al[61], 2012	163	MS 17 mo
Roeder et al[62], 2012	29	OS 3 yr 35%, LC 3 yr 18%
Haddock et al[63], 2017	158	OS 5 yr 16%
Holman et al[64], 2017	125	OS 3 and 5 yr 37% and 17%
PelvEx Collaborative et al[65], 2019	26	OS 5 yr 8.1%
Westberg et al[66], 2019	50	OS 3 yr 8%, OS 5 yr 4%

LC: Local control; MS: Median survival; OS: Overall survival.