Review
Copyright ©The Author(s) 2021.
World J Gastrointest Oncol. Sep 15, 2021; 13(9): 1029-1042
Published online Sep 15, 2021. doi: 10.4251/wjgo.v13.i9.1029
Table 2 Summary of the studies on involving lymph node detection in gastrointestinal cancer
Ref.
Patients
Detection rate
Sensitivity
Specificity
Considerations
Kusano et al[76], 200826 CRC, 22 GCCRC: 90.9%, GC: 88%CRC: S: 25%1, GS: 40%1Sp: 100%1, Sp: 100%1CRC: PPV: 100% NPV: 81%, GC: PPV: 100% NPV: 62.5%
Cahill et al[78], 2009891NR81%93.2%1PPV: 62% NPV: 95%. Lower FN if tumor size is less than 35 mm. IHC analysis increases sensitivity
Noura et al[58], 20102592%100%100%FNR: 0%. NPV: 100% Performed lateral pelvic dissection in order to increase SN detection accuracy
Kitagawa et al[80], 201339797.5%93.44%198.99%1Uses dual technique (blue dye and ICG)
Kinami et al[82], 20157290%98%1FN: 1.3%
Tummers et al[79], 20162695%75%88.9%Reduces second-tier nodes using nanocolloids
Lee et al[83], 20162095%100%94.4%FN: 0%
Villegas-Tovar et al[57], 202028191%64.3%65%AUC: 66.5%