Role of exosomal long non-coding RNAs in colorectal cancer

Table 1 Relationship between exosomal long non-coding RNAs and microRNAs in colorectal cancer

Exosomal lncRNA	Expression	miRNA	Target gene	Functions	Ref.
H19	↑	miR-141	β-catenin	Promotes the stemness and chemoresistance of CRC cells	Ren et al[37]
UCA1	↑	miR-143	MYO6	Promotes CRC cell proliferation and migration	Luan et al[38]
LINC00659	↑	miR-342-3p	ANXA2	Promotes CRC cell proliferation, invasion, and migration	Zhou et al[39]
MALAT1	↑	miR-26a/26b	FUT4	Promotes the metastasis of CRC	Xu et al[40]
HOTTIP	↑	miR-214	KPNA3	Increases resistance of CRC cells to mitomycin	Chen et al[41]
LINC02418	↑	miR-1273g-3p	MELK	Promotes the viability of CRC cells	Zhao et al[42]
GAS5	↑	miR-221	-	Promotes CRC cell proliferation	Liu et al[43]

LncRNA: Long non-coding RNA; CRC: Colorectal cancer; miRNAs: MicroRNAs.