High expression of protein phosphatase 2 regulatory subunit B'' alpha predicts poor outcome in hepatocellular carcinoma patients after liver transplantation

Table 2 Univariate analysis results of overall survival and tumor-free survival risk factors and patient characteristics

Variables	OS	RFS
	Univariate	Univariate
	P value	P value
PPP2R3A (< 4 vs ≥ 4)	0.0001	0.0251
Age (≤ 50 vs > 50)	0.122	0.213
Child-Pugh (≤ 6 vs 7-9 vs ≥ 10)	0.375	0.206
MELD (< 15 vs ≥ 15)	0.827	0.809
HBeAg (Negative vs Positive)	0.461	0.120
HBV-DNA (Negative vs Positive)	0.581	0.090
Pathology (Well vs Moderate vs Poor)	0.0471	< 0.051
Tumor number (1 vs > 1)	0.0001	0.0001
Tumor size (cm) (≤ 3 vs 4-5 vs ≥ 6)	0.0051	< 0.051
TNM-t (1 vs 2 vs 3)	0.0001	< 0.051
Microsatellite stove (No vs Yes)	0.0001	0.0001
Vascular invasion (No vs Yes)	0.011	0.0001
Lymph node metastasis (No vs Yes)	0.671	0.885
Capsule invasion (No vs Yes)	0.102	0.0051
Liver metastasis (No vs Yes)	0.124	0.0011
Chest metastasis (No vs Yes)	0.0011	0.0001
AFP (ng/mL) (< 13 vs 13-1000 vs > 1000)	0.0001	0.0001
Preoperative treatment (No vs Yes)	0.685	0.604

¹Statistically significant. OS: Overall survival; RFS: Recurrence-free survival; PPP2R3A: Protein phosphatase 2 regulatory subunit B''α; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus; AFP: Alpha-fetoprotein; TNM: Tumor-node-metastasis; MELD: Model for end-stage liver disease.