Predictive factors for early distant metastasis after neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Table 4 Predictive factors for early distant metastasis, n (%)

Characteristics	Early metastasis		P value
	Yes (n = 5)	No (n = 122)
Grade			0.025
Well differentiated	3 (60.0)	43 (35.2)
Moderately differentiated	1 (20.0)	77 (63.1)
Poorly differentiated	1 (20.0)	2 (1.6)
Tumor location			0.031
Distal	0	44 (36.1)
Mid	1 (20.0)	47 (38.5)
Proximal	4 (80.0)	31 (25.4)
MRF involvement			0.002
No	2 (40.0)	116 (95.1)
Yes	3 (60.0)	6 (4.9)
EMVI1			0.012
No	0	50 (58.1)
Yes	5 (100)	36 (41.9)

¹Patients who did not take magnetic resonance image of the rectum were excluded.

MRF: Mesorectal fascia; EMVI: Extramural venous invasion.