Should we resect colorectal cancer in patients over the age of 85?

Table 1 Demographic and comorbidity data on patients from 75-85 years old and those ≥ 85 years old

Feature	Number of 75-85 years old patients (% of 75-85 years old patients)	Number of ≥ 85 years old patients (% of ≥ 85 years old patients)	Total	P value
Patients	136	48	184
Gender
Male	66 (49)	15 (31)	81	0.043
Female	70 (51)	33 (69)	103
Median BMI	26	25
Range	15-40	16-40
< 20	2 (1)	2 (4)	4	0.14
20-24.9	44 (32)	24 (50)	67
25-29.9	50 (37)	16 (33)	65
30-39.9	31 (23)	5 (10)	36
> 40	9 (7)	1 (2)	10
ASA
Grade I	4 (3)	1 (2)	5	0.43
Grade II	29 (21)	8 (17)	37
Grade III	84 (62)	29 (60)	113
Grade IV	19 (14)	9 (19)	28
Grade V	0 (0)	1 (2)	1
Cardiac
Ischaemic heart disease	34 (25)	16 (34)	50	0.27
Coronary artery bypass graft	20 (15)	5 (11)	25	0.025
Percutaneous coronary intervention	9 (7)	4 (9)	13	0.75
Pacemaker insertion	4 (3)	0 (0)	4	0.57
Cardiac valve replacement	6 (4)	3 (6)	9	0.61
Heart failure (all types)	8 (6)	3 (6)	11	1.0
Cardiomyopathy	6 (4)	3 (6)	9	0.61
AICD insertion	1 (1)	1 (2)	2	0.44
Hypertension	85 (63)	34 (71)	119	0.38
Pulmonary hypertension	3 (2)	0 (0)	3	0.57
Atrial fibrillation	28 (21)	12 (25)	40	0.55
Respiratory
Asthma	21 (15)	4 (8)	25	0.33
COPD	22 (16)	4 (8)	26	0.23
Bronchiectasis	0 (0)	2 (4)	2	0.017
Cystic fibrosis	0 (0)	0 (0)	0	-
Obstructive sleep apnoea	10 (7)	0 (0)	10	0.066
Metabolic
Type I Diabetes	0 (0)	0 (0)	0	-
Type II Diabetes	27 (20)	11 (23)	38	0.68
Hyperlipidaemia	52 (38)	21 (44)	73	0.61
Previous cancer	31 (23)	10 (21)	11	0.78
Autoimmune
Rheumatoid arthritis	1 (1)	1 (2)	2	0.44
Psoraisis	5 (4)	1 (2)	6	0.59
Polymyalgia rheumatica	1 (1)	2 (4)	3	0.11
SLEII	1 (1)	0 (0)	1	0.55
Pre-operative renal function
eGFR > 90	46 (34)	12 (25)	58	0.007
eGFR 60-89	63 (46)	15 (31)	78
eGFR 45-59	18 (13)	15 (31)	33
eGFR 30-44	9 (7)	5 (11)	14
eGFR 15-29	0 (0)	1 (2)	1
eGFR < 15	0 (0)	0 (0)	0
Current smoker (within 12 mo)	7 (5)	1 (2)	8	0.68

BMI: Body mass index; ASA: American Society of Anaesthesiologists Physical Status Classifications; COPD: Chronic obstructive pulmonary disease; AICD: Automated implantable cardiac defibrillator; eGFR: Estimated glomerular filtration rate; SLE: Systemic lupus erythematosus.