Combination of neutrophil gelatinase-associated lipocalin and matrix metalloproteinase-9 are biomarkers for the detection of colon tubular adenocarcinoma

Figure 2 Expression of neutrophil gelatinase-associated lipocalin and matrix metalloproteinase-9 in tubular adenocarcinoma of the colon. A and B: The relative neutrophil gelatinase-associated lipocalin (NGAL) (A) and matrix metalloproteinase-9 (MMP-9) (B) gene expression in serum samples from normal tissues (n = 10) and patient tissues with different stages of tubular adenocarcinoma of the colon (From I to III) (n = 30); C and D: Western blotting analysis of the expression of NGAL (C) and MMP-9 (D) at the protein level. Three independent experiments were carried and analyzed. Data are expressed as mean values ± SE, ^bP < 0.01, two-tailed Student’s t-tests. NGAL: Neutrophil gelatinase-associated lipocalin; MMP-9: Matrix metalloproteinase-9.