Role of autophagy in gastric carcinogenesis

doi:10.4251/wjgo.v13.i10.1244

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Oct 15, 2021 (publication date) through Apr 23, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2021; 13(10): 1244-1262
Published online Oct 15, 2021. doi: 10.4251/wjgo.v13.i10.1244

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Figure 1 Autophagy activity pattern in normal and gastric malignant cells. Under normal conditions autophagy is strictly regulated in response to stimuli to preserve cytoplasm homeostasis. Excessive downregulation promotes gastric carcinogenesis and upon malignant transformation, the autophagic over activity contributes to progression, metastasis and negative prognosis. H. pylori: Helicobacter pylori.

Citation: Papaefthymiou A, Christodoulidis G, Koffas A, Doulberis M, Polyzos SA, Manolakis A, Potamianos S, Kapsoritakis A, Kountouras J. Role of autophagy in gastric carcinogenesis. World J Gastrointest Oncol 2021; 13(10): 1244-1262
URL: https://www.wjgnet.com/1948-5204/full/v13/i10/1244.htm
DOI: https://dx.doi.org/10.4251/wjgo.v13.i10.1244