Adjuvant chemotherapy in curatively resected rectal cancer: How valid are the data?

Table 3 Assessment of validity of the analyzed studies according to the CONSORT checklist

Section/topic	Item number	CCCSGJ[10] 1995	Krook et al[11] 1991	Quasar[12] 2007
Title and abstract	1a	Yes	No	Yes
	1b	No	Yes	Yes
Introduction
Background and objectives	2a	Yes	Yes	Yes
	2b	Yes	Yes	Yes
Methods
Trial design	3a	No	Yes	Yes
	3b	NA	NA	NA
Participants	4a	Yes	Yes	Yes
	4b	No	No	No
Interventions	5	Yes	Yes	Yes
Outcomes	6a	No	No	Yes
	6b	NA	NA	NA
Sample size	7a	No	No	Yes
	7b	NA	NA	No
Randomisation	8a	Yes	No	Yes
	8b	No	No	Yes
	9	No	No	Yes
	10	No	No	Yes
Blinding	11a	NA	NA	NA
	11b	No	No	No
Statistical methods	12a	Yes	Yes	Yes
	12b	No	Yes	Yes
Results
Participant flow	13a	Yes	No	Yes
	13b	Yes	Yes	Yes
Recruitment	14a	Yes	Yes	Yes
	14b	NA	NA	NA
Baseline data	15	Yes	Yes	Yes
Numbers analysed	16	Yes	Yes	Yes
Outcomes and estimaton	17a	No	Yes	Yes
	17b	No	No	Yes
Ancillary analysis	18	Yes	Yes	Yes
Harms	19	Yes	Yes	Yes
Discussion
Limitations	20	Yes	Yes	No
Generalisability	21	No	No	No
Interpretation	22	Yes	Yes	Yes
Other information
Registration	23	No	No	Yes
Protocol	24	No	No	No
Funding	25	No	No	Yes

NA: Not applicable.