Impact of preoperative chemoradiotherapy using concurrent S-1 and CPT-11 on long-term clinical outcomes in locally advanced rectal cancer

Table 2 Acute toxicity according to Common Terminology Criteria for Adverse Events 4.0, on patients receiving chemoradiotherapy, n (%)

Toxicity	n = 82
	Any Grade	Grade 3 or 4
Hematological toxicity
Neutropenia	56 (68.3)	16 (19.5)
Leukopenia	59 (72.0)	15 (18.3)
Febrile neutropenia	3 (3.6)	3 (3.6)
Thrombocytopenia	11 (13.4)	0
Nonhematological toxicity
Diarrhea	53 (64.6)	22 (26.8)
Anorexia	20 (24.4)	1 (1.2)
Fatigue	15 (18.3)	0
Nausea	13 (15.9)	0