Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer

doi:10.4251/wjgo.v12.i12.1428

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World Journal of Gastrointestinal Oncology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2020; 12(12): 1428-1442
Published online Dec 15, 2020. doi: 10.4251/wjgo.v12.i12.1428

Table 2 Pathological results and tumor response to neoadjuvant treatment (n = 86)¹

	n (%)
ypT
0	13 (15)
1	3 (3.8)
2	12 (13.8)
3	46 (53.4)
4	12 (14)
ypN
0	72 (83.8)
1	10 (11.6)
2	4 (4.6)
Median number of resected nodes²	9 (2-26)
Median number of involved nodes²	0 (0-8)
Lymphovascular invasion
Positive	15 (17.4)
Negative	71 (82.6)
Perineural invasion
Positive	22 (25.5)
Negative	64 (74.5)
Resection margin
Positive	7 (8.1)
Negative	79 (91.9)
Pathologic complete response
Yes	12 (14)
No	74 (86)
Tumor regression grade
0	13 (15.1)
1	30 (34.9)
2	27 (31.4)
3	16 (18.6)
Pathologic T stage
Downstaging	74 (86)
Stable	112 (14)
Progressive	0 (0)
Pathologic N stage
Downstaging	75 (87.3)
Stable	7 (8.1)
Progressive	4 (4.6)

¹Two patients (T4bN2M0 and T4aN2M0) did not undergo surgical resection.

²Median (range).

Citation: Huang CM, Huang CW, Ma CJ, Tsai HL, Su WC, Chang TK, Huang MY, Wang JY. Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer. World J Gastrointest Oncol 2020; 12(12): 1428-1442
URL: https://www.wjgnet.com/1948-5204/full/v12/i12/1428.htm
DOI: https://dx.doi.org/10.4251/wjgo.v12.i12.1428