Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer

doi:10.4251/wjgo.v12.i12.1428

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Dec 15, 2020 (publication date) through Apr 28, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Gastrointest Oncol. Dec 15, 2020; 12(12): 1428-1442
Published online Dec 15, 2020. doi: 10.4251/wjgo.v12.i12.1428

Table 1 Patient and treatment characteristics (n = 88), n (%)

Characteristic	n = 88
Age, median (yr, range)	63 (34-93)
Sex
Male	42 (47.7)
Female	46 (52.3)
Location
Colon	25 (28.4)
Rectum	63 (71.6)
cT stage
T4a	44 (50)
T4b	44 (50)
cN stage
N0	7 (8)
N1	37 (42)
N2	44 (50)
cTNM stage
II	6 (6.8)
III	82 (93.2)
Tumor grade
Well differentiated	4 (4.6)
Moderately differentiated	72 (81.8)
Poorly differentiated	12 (13.6)
Pretreatment CEA (ng/mL)
≤ 5	46 (52.3)
> 5	42 (47.7)
Preoperative chemotherapy
FOLFOX	75 (85.2)
Capecitabine	13 (14.8)
Radiation technique
Tomotherapy	24 (27.9)
Volumetric arc therapy	49 (57)
Conformal radiotherapy	15 (15.1)
Radiation dose (Gy)
< 50	26 (29.5)
≥ 50	62 (70.5)
Radiation-surgery interval (wk, range)	9 (5-40)

CEA: Carcinoembryonic antigen.

Citation: Huang CM, Huang CW, Ma CJ, Tsai HL, Su WC, Chang TK, Huang MY, Wang JY. Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer. World J Gastrointest Oncol 2020; 12(12): 1428-1442
URL: https://www.wjgnet.com/1948-5204/full/v12/i12/1428.htm
DOI: https://dx.doi.org/10.4251/wjgo.v12.i12.1428