Hepatic resection vs percutaneous radiofrequency ablation of hepatocellular carcinoma abutting right diaphragm

Table 2 Univariate and multivariate analysis of prognostic factors for overall survival

Variable	Univariate analysis		Multivariate analysis
	HR	P value	HR	P value
Group (RF ablation)	0.364 (0.179, 0.742)	0.005	0.676 (0.309, 1.482)	0.329
Age	1.025 (0.988, 1.063)	0.187
Sex (female)	0.975 (0.439, 2.165)	0.95
Etiology (hepatitis B virus)1		0.028		0.176
Hepatitis C virus	3.053 (1.240, 7.516)	0.01	2.180 (0.854, 5.566)	0.124
NBNC	2.292 (0.671, 7.831)	0.26	2.433 (0.686, 8.636)	0.232
Liver cirrhosis (absence)	1.834 (0.756, 4.446)	0.18
Tumor size	1.505 (0.782, 2.899)	0.221
α-fetoprotein	1.000 (1.000, 1.001)	0.345
Platelet count	0.989 (0.982, 0.996)	0.003	0.991 (0.982, 1.000)	0.051
Alanine aminotransferase	1.006 (0.993, 1.019)	0.36
Total bilirubin	1.031 (0.393, 2.704)	0.951
Albumin	0.327 (0.148, 0.727)	0.006	0.485 (0.189, 1.244)	0.132
Prothrombin time (INR)	19.351 (1.354, 1798.539)	0.034	0.325 (0.002, 46.731)	0.657

The Cox proportional hazards model was used for univariate and multivariate analysis. The reference category for each categorical variable is provided in the square brackets in the first column.

¹Bonferroni correction was used owing to multiple comparisons. Numbers in parentheses represent the 95%CI. HR: Hazard ratio; RF: Radiofrequency; NBNC: Non-B non-C; INR: International normalized ratio.