Histo-molecular oncogenesis of pancreatic cancer: From precancerous lesions to invasive ductal adenocarcinoma

doi:10.4251/wjgo.v10.i10.317

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2018; 10(10): 317-327
Published online Oct 15, 2018. doi: 10.4251/wjgo.v10.i10.317

Table 1 Immunohistochemical markers for intraductal papillary mucinous neoplasm/intraductal tubulo-papillary neoplasm histopathological classification

Type of lesion	Subtype	MUC1	MUC2	MUC5AC	MUC6	CDX2
IPMN	G	Negative	Negative	Positive¹	Negative	Negative
	PB	Positive¹	Negative	Positive¹	Positive	Negative
	INT	Negative	Positive¹	Positive¹	Negative	Positive¹
	ONC	Positive	Negative	Positive	Positive¹	Negative
ITPN		Positive	Negative	Negative	Positive¹	Negative

IPMN: Intraductal papillary mucinous neoplasm; ITPN: Intraductal tubulo-papillary neoplasm; G: Gastric; PB: Pancreaticobiliary; INT: Intestinal; ONC: Oncocytic.

¹The positivity of a marker is very intense at the immunohistochemical level (++).

Citation: Riva G, Pea A, Pilati C, Fiadone G, Lawlor RT, Scarpa A, Luchini C. Histo-molecular oncogenesis of pancreatic cancer: From precancerous lesions to invasive ductal adenocarcinoma. World J Gastrointest Oncol 2018; 10(10): 317-327
URL: https://www.wjgnet.com/1948-5204/full/v10/i10/317.htm
DOI: https://dx.doi.org/10.4251/wjgo.v10.i10.317