Comparison between laparoscopic and open surgery for large gastrointestinal stromal tumors: A meta-analysis

Table 1 Main characteristics of enrolled trials

Ref.	Region	Year	Study design	Study period	Sample size		Tumor size (cm)		CS	Follow-up (mo)
					LAP	Open	LAP	Open
Kim et al[10]	South Korea	2012	OCS (R)	1998-2011	24	14	6.1 ± 1.3	7.2 ± 1.7	0	49.3 (8.4-164.4)
Lin et al[11]	China	2014	OCS (R)	2007-2012	23	23	7.2 ± 1.6	7.3 ± 1.5	1	34.0 (6-78)
Hsiao et al[12]	Taiwan	2015	OCS (P)	2002-2012	18	37	6.1 ± 1.0	6.0 ± 0.9	0	43.2 (16.8-133.2)
Takahashi et al[13]	Japan	2015	OCS (R)	1995-2011	12	15	7.5 ± 1.9	5.5 ± 0.73	3	63 (7-154)
Khoo et al[14]	Japan	2016	OCS (R)	2002-2015	23	36	NA	NA	1	45

OCS: Observational clinical study; R: Retrospective study; P: Prospective study; NA: Not available; CS: Convention surgery.