Effectiveness of fecal DNA syndecan-2 methylation testing for detection of colorectal cancer in a high-risk Chinese population

doi:10.4251/wjgo.v16.i4.1361

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Apr 15, 2024 (publication date) through May 14, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2024; 16(4): 1361-1373
Published online Apr 15, 2024. doi: 10.4251/wjgo.v16.i4.1361

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Figure 1 Screening process flow chart. mSDC: Syndecan-2 methylation; CRC: Colorectal cancer; AA: Advanced adenoma; NAA: Non-advanced adenoma; Polyps: Non-adenomatous polyps; Others: Totally normal colonoscopy, colitis and colonic diverticulum, etc.

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Figure 2 Receiver operating characteristic curve of fecal occult-blood and syndecan-2 methylation tests for detection of colorectal cancer, advanced adenoma and advanced colorectal neoplasia. A: Colorectal cancer; B: Advanced adenoma; C: Advanced colorectal neoplasia. SCD2: Syndecan-2; FOBT: Fecal occult-blood; AUC: Area under the receiver operating characteristic curve.

Citation: Luo WF, Jiao YT, Lin XL, Zhao Y, Wang SB, Shen J, Deng J, Ye YF, Han ZP, Xie FM, He JH, Wan Y. Effectiveness of fecal DNA syndecan-2 methylation testing for detection of colorectal cancer in a high-risk Chinese population. World J Gastrointest Oncol 2024; 16(4): 1361-1373
URL: https://www.wjgnet.com/1948-5204/full/v16/i4/1361.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i4.1361